ZNF562

Across TCGA patient cohorts, ZNF562 mutation is significantly associated with the RNA expression of many other genes, with 406 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF562-associated genes across cancer lineages are GCNT1P2, PRY2, and RNA5SP325. Each is linked with ZNF562 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF562-to-partner and partner-to-ZNF562 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GCNT1P2 grouped by ZNF562-low versus ZNF562-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF562→partner) and Y-score (partner→ZNF562) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	GCNT1P2 →	+0.147	+5.159	<.001	.007	3	2
ESCA	PRY2 →	+0.050	+6.303	<.001	<.001	3	2
ESCA	RNA5SP325 →	+0.529	+4.392	<.001	.006	3	2
ESCA	RNA5SP205 →	+0.848	+4.392	<.001	.006	3	2
ESCA	RNA5SP239 →	+0.412	+4.564	<.001	.004	3	2
ESCA	MRPS18BP1 →	+0.197	+4.681	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 406 associations by consensus.

GCNT1P2 by ZNF562 expression — SKCM

Explore this box plot interactively →