ZNF561

Across TCGA patient cohorts, ZNF561 protein abundance is significantly associated with the RNA expression of many other genes, with 769 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF561-associated genes across cancer lineages are RNASEH2A, ZNF317, and SGK2. Each is linked with ZNF561 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF561-to-partner and partner-to-ZNF561 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF561 versus RNASEH2A in LSCC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF561→partner) and Y-score (partner→ZNF561) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RNASEH2A →	+0.307	+0.547	.004	<.001	3	2
LSCC	ZNF317 →	+0.499	+0.483	<.001	<.001	3	2
UCEC	SGK2 →	+2.197	+0.837	<.001	.002	3	1
UCEC	HAVCR1 →	+3.865	+0.790	.005	.003	3	1
UCEC	GON4L →	-0.585	-0.607	.006	.008	3	1
UCEC	KDM5B →	-0.950	-0.762	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 769 associations by consensus.

ZNF561 vs RNASEH2A — LSCC

Explore this scatter interactively →