ZNF561

Across TCGA cell cohorts, ZNF561 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,423 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF561-associated GO terms across cancer lineages are Negative regulation of chromosome condensation, Heterochromatin formation, and Heterochromatin organization. Each is linked with ZNF561 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZNF561-to-partner and partner-to-ZNF561 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chromosome condensation grouped by ZNF561-low versus ZNF561-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF561→partner) and Y-score (partner→ZNF561) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of chromosome condensation →	+0.110	+0.753	<.001	<.001	3	13
OVARY	Heterochromatin formation →	+0.061	+0.660	<.001	<.001	2	12
OVARY	Heterochromatin organization →	+0.056	+0.597	<.001	.003	2	11
OVARY	Epigenetic regulation of gene expression →	+0.056	+0.761	<.001	<.001	3	10
URINARY_TRACT	Positive regulation of mRNA catabolic process →	+0.075	+0.985	<.001	<.001	3	10
BREAST	DNA-templated transcription elongation →	+0.061	+0.730	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,423 associations by consensus.

Negative regulation of chromosome condensation by ZNF561 expression — SOFT_TISSUE

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