ZNF561

Across TCGA cell cohorts, ZNF561 mutation is significantly associated with the RNA expression of many other genes, with 105 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF561-associated genes across cancer lineages are REG1B, CXorf51A, and OR4X2. Each is linked with ZNF561 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF561-to-partner and partner-to-ZNF561 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REG1B grouped by ZNF561-low versus ZNF561-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF561→partner) and Y-score (partner→ZNF561) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	REG1B →	+0.025	+5.000	<.001	.006	3	1
PANCREAS	CXorf51A →	+0.083	+5.614	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR4X2 →	+0.014	+3.362	<.001	.007	3	1
LUNG_NSCLC_LUAD	OR1D2 →	+0.013	+4.266	<.001	.004	3	1
LUNG_NSCLC_LUAD	RBMY1D →	+0.118	+3.604	<.001	.004	3	1
LARGE_INTESTINE	PHF5A →	+0.581	+3.364	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 105 associations by consensus.

REG1B by ZNF561 expression — PANCREAS

Explore this box plot interactively →