ZNF558

Across TCGA patient cohorts, ZNF558 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,838 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF558-associated proteins across cancer lineages are TNPO2, CARM1, and XAB2. Each is linked with ZNF558 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF558-to-partner and partner-to-ZNF558 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF558 versus TNPO2 in LSCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF558→partner) and Y-score (partner→ZNF558) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TNPO2 →	+0.358	+0.583	<.001	<.001	3	6
OV	CARM1 →	+0.374	+0.779	<.001	<.001	3	6
LSCC	XAB2 →	+0.268	+0.496	<.001	<.001	3	6
LSCC	THOC2 →	+0.310	+0.525	<.001	<.001	3	5
GBM	MVB12A →	+0.310	+0.498	<.001	<.001	3	5
LSCC	ADNP →	+0.426	+0.684	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,838 associations by consensus.

ZNF558 vs TNPO2 — LSCC

Explore this scatter interactively →