Q-omics provides the consensus-scored ZNF555 profile across patient tissues and cancer cell-line models. ZNF555 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, ZNF555 is differentially expressed in 9, with the highest sampling consensus in THCA. Additionally, ZNF555 RNA expression shows 20,277 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KIRC, THCA, and THYM as cancer lineages where ZNF555 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ZNF555 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ZNF555 survival associations across molecular data types. ZNF555 RNA expression shows survival associations in the most cancer types (24), followed by mutation status (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ZNF555 RNA expression–survival associations across cancer types. High ZNF555 expression shows favorable associations in KIRC, LUAD, UCEC, LAML, HNSC and PAAD. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for ZNF555 RNA expression.
This table summarizes ZNF555 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for ZNF555. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ZNF555 shows lower tumor expression in THCA, UCEC, KIRC, LUAD and LUSC and higher tumor expression in LIHC. The THCA box plot shows higher ZNF555 RNA expression in normal versus tumor tissue (log2 FC = −0.731, t-test p < 0.001).
This table shows molecular features associated with ZNF555 in patient tissues and cancer cell lines. In patient samples, ZNF555 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set. In cancer cell lines, ZNF555 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in LIVER, while CRISPR and shRNA rows add functional-dependency signals in BLOOD_Lymphoma and LARGE_INTESTINE.
