Across TCGA cell cohorts, ZNF551 mutation is significantly associated with the mutation status of many other genes, with 4,389 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF551-associated genes across cancer lineages are GAS2L2, ZNF141, and MYH10. Each is linked with ZNF551 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF551-to-partner and partner-to-ZNF551 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF551→partner) and Y-score (partner→ZNF551) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GAS2L2 →	+3.285	+4.209	<.001	<.001	1	3
CNS	ZNF141 →	+4.459	+5.277	.005	.005	1	3
CNS	MYH10 →	+4.459	+5.277	.005	.005	1	3
SKIN	ZNF646 →	+3.035	+3.321	.008	.008	1	3
SKIN	HCFC1 →	+3.357	+3.532	.005	.005	1	3
SKIN	OPLAH →	+3.772	+3.772	.003	.003	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,389 associations by consensus.

Exploration

ZNF551 survival (RNA) · tumor vs normal (RNA) · all ZNF551 data types