ZNF550

Across TCGA pan-cancer cohorts, ZNF550 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated ZNF550 data layer compared with 27 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher ZNF550 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF550 expression acts as an unfavorable survival marker.

COAD, BRCA, and UCEC are the cancer types where ZNF550 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.019	0.791	<.001	12	view →
BRCA	OS	Median	All	0.676	0.963	.015	10	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

ZNF550–COAD (DFS)

Open the COAD breakdown →