ZNF550

Across TCGA cell cohorts, ZNF550 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,171 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF550-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Spliceosomal complex assembly. Each is linked with ZNF550 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF550-to-partner and partner-to-ZNF550 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ZNF550-low versus ZNF550-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF550→partner) and Y-score (partner→ZNF550) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of myoblast fusion →	+0.107	+0.924	<.001	<.001	3	17
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.101	+1.045	<.001	<.001	3	17
LUNG_SCLC	Spliceosomal complex assembly →	+0.081	+0.824	<.001	.002	3	16
STOMACH	Regulation of myoblast fusion →	+0.118	+1.288	<.001	<.001	3	16
SOFT_TISSUE	Regulation of organelle assembly →	+0.035	+0.597	.003	.005	3	15
SOFT_TISSUE	Late viral transcription →	+0.130	+0.793	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,171 associations by consensus.

Negative regulation of myoblast fusion by ZNF550 expression — BREAST

Explore this box plot interactively →