ZNF547

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF547 mutation is significantly associated with the RNA expression of many other genes, with 3,625 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF547-associated genes across cancer lineages are RNA5SP412, MIR4633, and ULK4P1. Each is linked with ZNF547 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF547-to-partner and partner-to-ZNF547 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by ZNF547-low versus ZNF547-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF547→partner) and Y-score (partner→ZNF547) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP412 →+0.426+1.493<.001.00932
LUADMIR4633 →+0.597+4.191.001.00432
COADULK4P1 →+0.053+4.271<.001.00332
HNSCBNIP3P4 →+0.102+5.822<.001.00332
HNSCMIR6508 →+0.672+5.655<.001.00432
SKCMTUBB8P5 →+0.040+4.208<.001.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,625 associations by consensus.

RNA5SP412 by ZNF547 expression — UCEC

Box plot of RNA5SP412 in ZNF547-low vs ZNF547-high samples in UCEC.

Explore this box plot interactively →

Exploration