ZNF547

Across TCGA cell cohorts, ZNF547 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF547-associated genes across cancer lineages are RNASE9, C9orf57, and GNG8. Each is linked with ZNF547 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF547-to-partner and partner-to-ZNF547 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNASE9 grouped by ZNF547-low versus ZNF547-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF547→partner) and Y-score (partner→ZNF547) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	RNASE9 →	+0.009	+4.415	<.001	.007	3	1
SKIN	C9orf57 →	+0.009	+4.415	<.001	.007	3	1
LUNG_NSCLC_LUAD	GNG8 →	+0.268	+4.887	.001	.009	3	1
LUNG_NSCLC_LUAD	MS4A13 →	+0.325	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR4C12 →	+0.022	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR4M2 →	+0.267	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

RNASE9 by ZNF547 expression — SKIN

Explore this box plot interactively →