ZNF547

Across TCGA cell cohorts, ZNF547 mutation is significantly associated with the mutation status of many other genes, with 4,530 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF547-associated genes across cancer lineages are TDRD6, PTCH1, and ZNF407. Each is linked with ZNF547 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF547-to-partner and partner-to-ZNF547 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TDRD6 grouped by ZNF547-low versus ZNF547-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF547→partner) and Y-score (partner→ZNF547) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	TDRD6 →	+2.977	+4.273	.006	.006	1	4
OVARY	PTCH1 →	+3.240	+4.467	.004	.004	1	4
OVARY	ZNF407 →	+3.240	+4.467	.004	.004	1	4
LARGE_INTESTINE	SPOCD1 →	+2.321	+2.643	.004	.004	1	4
LARGE_INTESTINE	PLCB3 →	+1.932	+2.693	.004	.004	1	4
BLOOD_Leukemia	ITPKC →	+4.321	+5.285	.005	.005	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,530 associations by consensus.

TDRD6 by ZNF547 expression — OVARY

Explore this box plot interactively →