Across TCGA patient cohorts, ZNF534 mutation is significantly associated with the RNA expression of many other genes, with 4,127 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF534-associated genes across cancer lineages are ZFYVE19, EIF3JP1, and PPIAL4F. Each is linked with ZNF534 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF534-to-partner and partner-to-ZNF534 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF534→partner) and Y-score (partner→ZNF534) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZFYVE19 →	+0.399	+2.526	<.001	.001	3	3
LIHC	EIF3JP1 →	+0.130	+4.544	<.001	.009	3	3
LUAD	PPIAL4F →	+0.094	+3.357	<.001	.007	3	3
COAD	THAP3 →	+0.344	+3.499	.002	.002	3	3
COAD	ITGAE →	+0.676	+3.486	<.001	.002	3	3
UCEC	PKN3 →	+0.869	+2.711	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,127 associations by consensus.

Exploration

ZNF534 survival (RNA) · tumor vs normal (RNA) · all ZNF534 data types