Across TCGA cell cohorts, ZNF534 mutation is significantly associated with the RNA expression of many other genes, with 599 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF534-associated genes across cancer lineages are C1orf185, PRRG3, and KRTAP1-5. Each is linked with ZNF534 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF534-to-partner and partner-to-ZNF534 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF534→partner) and Y-score (partner→ZNF534) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	C1orf185 →	+0.065	+4.584	<.001	.001	3	1
BLOOD_Leukemia	PRRG3 →	+0.012	+4.922	<.001	.009	3	1
BLOOD_Leukemia	KRTAP1-5 →	+0.030	+4.922	.003	.009	3	1
LARGE_INTESTINE	PLA2G3 →	+1.172	+3.347	<.001	.005	3	1
LARGE_INTESTINE	ANKRD54 →	+0.479	+3.299	.007	.004	3	1
LARGE_INTESTINE	CBY1 →	+0.730	+3.299	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 599 associations by consensus.

Exploration

ZNF534 survival (RNA) · tumor vs normal (RNA) · all ZNF534 data types