ZNF528-AS1

Across TCGA pan-cancer cohorts, ZNF528-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ZNF528-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher ZNF528-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ZNF528-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and OV show a favorable association.

UCS, LGG, and READ are the cancer types where ZNF528-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Median	II,III,IV	0.529	0.277	.023	56	view →
LGG	DFS	Quartile	All	0.610	0.805	<.001	28	view →
READ	DFS	Tertile	II,III,IV	0.668	0.912	.002	28	view →
OV	OS	Quartile	IV	0.751	0.391	.003	26	view →
LUSC	DFS	Quartile	III,IV	0.200	0.525	.005	23	view →
BLCA	DFS	Median	II,III,IV	0.552	0.462	.027	16	view →
SARC	DFS	Tertile	All	0.313	0.570	.002	13	view →
CESC	OS	Median	IV	0.784	0.372	.014	12	view →
PRAD	DFS	Tertile	All	0.704	0.896	.010	12	view →
LIHC	DFS	Median	All	0.315	0.506	.014	8	view →
THYM	DFS	Quartile	All	1.000	0.632	.023	7	view →
KIRC	DFS	Tertile	II,III,IV	0.397	0.579	.007	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ZNF528-AS1–UCS (OS)

Open the UCS breakdown →