ZNF528-AS1

Across TCGA pan-cancer cohorts, ZNF528-AS1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of ZNF528-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where ZNF528-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF528-AS1 is over-expressed in tumor, although a few such as COAD and KICH show the opposite, repressed pattern.

COAD, KICH, and CHOL are the cancer types where ZNF528-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF528-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	−0.393	<.001	8	view →
KICH	Male	All	−0.828	<.001	5	view →
CHOL	All	All	+1.630	.002	4	view →
LIHC	All	All	+0.350	<.001	4	view →
PRAD	All	All	+0.469	<.001	2	view →
ESCA	Female	All	−1.493	.009	1	view →
THCA	Male	IV	−0.346	.030	1	view →
LUSC	Male	All	−0.303	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

ZNF528-AS1–COAD

Open the COAD breakdown →