Across TCGA patient cohorts, ZNF525 mutation is significantly associated with the RNA expression of many other genes, with 4,859 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF525-associated genes across cancer lineages are TAF13, RRM2, and RBFA. Each is linked with ZNF525 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF525-to-partner and partner-to-ZNF525 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF525→partner) and Y-score (partner→ZNF525) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TAF13 →	+0.649	+3.741	<.001	<.001	3	4
UCEC	RRM2 →	+0.630	+1.645	<.001	<.001	3	4
COAD	RBFA →	+0.347	+2.502	.002	.002	3	4
UCEC	NUSAP1 →	+0.620	+1.547	<.001	<.001	3	4
SKCM	RCC1 →	+0.604	+3.006	<.001	<.001	3	4
SKCM	DCLRE1B →	+0.574	+2.341	.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,859 associations by consensus.

Exploration

ZNF525 survival (RNA) · tumor vs normal (RNA) · all ZNF525 data types