ZNF519

Across TCGA cell cohorts, ZNF519 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,473 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF519-associated GO terms across cancer lineages are Negative regulation of cell cycle process, Mitotic nuclear division, and Spindle assembly. Each is linked with ZNF519 in more than 19 cancer types. Because this analysis shows association rather than direction, both ZNF519-to-partner and partner-to-ZNF519 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell cycle process grouped by ZNF519-low versus ZNF519-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF519→partner) and Y-score (partner→ZNF519) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of cell cycle process →	+0.095	+1.520	.001	<.001	3	20
LUNG_NSCLC_LUSC	Mitotic nuclear division →	+0.115	+1.398	<.001	.003	3	20
BONE	Spindle assembly →	+0.114	+1.437	.001	.001	3	20
PANCREAS	Regulation of chromosome segregation →	+0.135	+1.242	<.001	<.001	3	20
BONE	Double-strand break repair →	+0.108	+1.568	<.001	<.001	3	20
PANCREAS	DNA recombination →	+0.082	+0.929	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,473 associations by consensus.

Negative regulation of cell cycle process by ZNF519 expression — BONE

Explore this box plot interactively →