ZNF513

Across TCGA patient cohorts, ZNF513 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF513-associated genes across cancer lineages are ATM, Caspase-7-cleavedD198, and EGFR_pY1068. Each is linked with ZNF513 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF513-to-partner and partner-to-ZNF513 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by ZNF513-low versus ZNF513-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF513→partner) and Y-score (partner→ZNF513) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.636	-2.222	<.001	.011	3	2
UCEC	Caspase-7-cleavedD198 →	+0.745	+3.479	.003	.002	3	2
UCEC	EGFR_pY1068 →	-0.246	-2.321	.020	.034	3	1
UCEC	GAPDH →	+0.509	+3.321	.025	.009	3	1
UCEC	GATA6 →	-0.197	-1.992	.004	.031	3	1
UCEC	IGFBP2 →	-0.561	-1.700	.042	.044	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

ATM by ZNF513 expression — UCEC

Explore this box plot interactively →