ZNF513

Across TCGA pan-cancer cohorts, ZNF513 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated ZNF513 data layer compared with 4 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ZNF513 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF513 expression acts as an unfavorable survival marker, although some lineages such as SCLC and BLCA show a favorable association.

KIRC, ACC, and UVM are the cancer types where ZNF513 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	All	0.481	0.675	<.001	154	view →
ACC	DFS	Median	All	0.228	0.622	<.001	142	view →
UVM	OS	Median	III,IV	0.393	0.946	<.001	107	view →
SCLC	OS	Tertile	II,III,IV	0.737	0.238	<.001	81	view →
LIHC	DFS	Tertile	All	0.414	0.613	<.001	66	view →
COAD	DFS	Median	All	0.432	0.621	<.001	47	view →
SKCM	DFS	Median	All	0.658	0.850	<.001	36	view →
UCS	OS	Median	IV	0.302	0.817	.002	36	view →
BLCA	OS	Quartile	II,III,IV	0.593	0.335	.007	28	view →
ESCA	DFS	Median	III,IV	0.269	0.571	<.001	24	view →
PRAD	DFS	Median	All	0.835	0.930	<.001	18	view →
DLBC	DFS	Median	All	0.629	1.000	.017	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

ZNF513–KIRC (DFS)

Open the KIRC breakdown →