ZNF513

Across TCGA cell cohorts, ZNF513 mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF513-associated genes across cancer lineages are OR10R2, SCGB2A1, and TRMT10A. Each is linked with ZNF513 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF513-to-partner and partner-to-ZNF513 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10R2 grouped by ZNF513-low versus ZNF513-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF513→partner) and Y-score (partner→ZNF513) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR10R2 →	+0.016	+5.472	<.001	<.001	3	2
LARGE_INTESTINE	SCGB2A1 →	+0.439	+3.392	.001	.006	3	1
LARGE_INTESTINE	TRMT10A →	+0.789	+3.082	<.001	.007	3	1
LARGE_INTESTINE	SEPTIN14 →	+0.005	+2.777	.003	.004	3	1
LARGE_INTESTINE	ITGAD →	+0.010	+2.832	<.001	.002	3	1
LARGE_INTESTINE	FAM205A →	+0.014	+2.444	.003	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

OR10R2 by ZNF513 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →