ZNF510

Across TCGA patient cohorts, ZNF510 mutation is significantly associated with the RNA expression of many other genes, with 2,490 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF510-associated genes across cancer lineages are RNU6-85P, TOMM22P5, and CDC27P1. Each is linked with ZNF510 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF510-to-partner and partner-to-ZNF510 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-85P grouped by ZNF510-low versus ZNF510-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF510→partner) and Y-score (partner→ZNF510) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-85P →	+0.507	+4.399	<.001	.006	3	4
UCEC	TOMM22P5 →	+0.149	+1.756	.002	.001	3	3
SKCM	CDC27P1 →	+0.085	+4.135	.001	.004	3	2
UCEC	MIR3690 →	+0.311	+1.934	<.001	.001	3	2
BLCA	RNU1-91P →	+0.278	+3.317	.002	.008	3	2
BLCA	MIR597 →	+0.211	+4.038	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,490 associations by consensus.

RNU6-85P by ZNF510 expression — COAD

Explore this box plot interactively →