ZNF503

Across TCGA cell cohorts, ZNF503 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible ZNF503-associated genes across cancer lineages are FSHR, SPATA31A5, and IGSF21. Each is linked with ZNF503 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF503-to-partner and partner-to-ZNF503 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FSHR grouped by ZNF503-low versus ZNF503-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF503→partner) and Y-score (partner→ZNF503) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	FSHR →	+0.083	+4.947	<.001	.001	3	1
LUNG_NSCLC_LUAD	SPATA31A5 →	+0.009	+4.662	<.001	.005	3	1
SKIN	IGSF21 →	+1.766	+4.095	<.001	.009	3	1
SKIN	NKX6-3 →	+0.030	+4.930	<.001	.001	3	1
SKIN	C10orf71 →	+0.004	+4.415	<.001	.007	3	1
SKIN	OTOP3 →	+0.013	+4.930	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

FSHR by ZNF503 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →