ZNF500

Across TCGA patient cohorts, ZNF500 protein abundance is significantly associated with the RNA expression of many other genes, with 1,051 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZNF500-associated genes across cancer lineages are RBM33, XPC-AS1, and RBM14. Each is linked with ZNF500 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF500-to-partner and partner-to-ZNF500 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF500 versus RBM33 in GBM, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF500→partner) and Y-score (partner→ZNF500) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RBM33 →	+0.654	+0.507	.008	<.001	3	2
BRCA	XPC-AS1 →	+0.760	+1.362	.003	.007	3	2
GBM	RBM14 →	+0.709	+0.507	.009	<.001	3	2
GBM	TFAP2E-AS1 →	+0.905	+0.507	.007	<.001	3	2
BRCA	PGS1 →	+0.700	+1.106	.003	.007	3	2
OV	SLC25A36 →	-0.722	-1.015	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,051 associations by consensus.

ZNF500 vs RBM33 — GBM

Explore this scatter interactively →