ZNF487

Across TCGA cell cohorts, ZNF487 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ZNF487-associated genes across cancer lineages are MS4A10, CBLL2, and LCE1C. Each is linked with ZNF487 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF487-to-partner and partner-to-ZNF487 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A10 grouped by ZNF487-low versus ZNF487-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF487→partner) and Y-score (partner→ZNF487) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	MS4A10 →	+0.013	+5.196	<.001	.005	3	1
OVARY	CBLL2 →	+0.025	+5.196	<.001	.005	3	1
OVARY	LCE1C →	+0.058	+5.196	<.001	.005	3	1
LUNG_NSCLC_LUAD	GJA8 →	+0.590	+3.734	<.001	.006	3	1
LUNG_NSCLC_LUAD	OCSTAMP →	+0.020	+4.343	<.001	.002	3	1
LUNG_NSCLC_LUAD	SSX5 →	+0.776	+4.343	.006	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

MS4A10 by ZNF487 expression — OVARY

Explore this box plot interactively →