ZNF483

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF483 protein abundance is significantly associated with the RNA expression of many other genes, with 442 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF483-associated genes across cancer lineages are MYBL2, CDS2, and SYTL4. Each is linked with ZNF483 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF483-to-partner and partner-to-ZNF483 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF483 versus MYBL2 in GBM, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF483→partner) and Y-score (partner→ZNF483) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMMYBL2 →-1.009-0.384.002.00231
GBMCDS2 →+0.366+0.523.005.00131
GBMSYTL4 →+0.805+0.396.004.00631
GBMOIP5 →-0.635-0.487.001.00231
GBMMCM4 →-0.878-0.558<.001<.00131
GBMKIR3DX1 →+0.137+0.486<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 442 associations by consensus.

ZNF483 vs MYBL2 — GBM

Per-sample scatter of ZNF483 vs MYBL2 in GBM (Pearson r = -0.36).

Explore this scatter interactively →

Exploration