ZNF483

Across TCGA cell cohorts, ZNF483 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,961 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF483-associated GO terms across cancer lineages are Protein K11-linked ubiquitination, Protein localization to nucleus, and RNA localization. Each is linked with ZNF483 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZNF483-to-partner and partner-to-ZNF483 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein K11-linked ubiquitination grouped by ZNF483-low versus ZNF483-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF483→partner) and Y-score (partner→ZNF483) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Protein K11-linked ubiquitination →	+0.068	+0.560	<.001	<.001	3	13
OVARY	Protein localization to nucleus →	+0.060	+0.775	<.001	<.001	3	13
SOFT_TISSUE	RNA localization →	+0.102	+0.843	<.001	<.001	3	12
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.081	+1.070	<.001	<.001	3	12
LUNG_SCLC	Negative regulation of gene expression, epigenetic →	+0.074	+0.918	<.001	.001	3	12
SOFT_TISSUE	Microtubule polymerization or depolymerization →	+0.067	+0.493	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,961 associations by consensus.

Protein K11-linked ubiquitination by ZNF483 expression — LARGE_INTESTINE

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