Across TCGA cell cohorts, ZNF480 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF480-associated genes across cancer lineages are SYCP1, GGTLC2, and SYT10. Each is linked with ZNF480 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF480-to-partner and partner-to-ZNF480 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF480→partner) and Y-score (partner→ZNF480) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SYCP1 →	+0.159	+4.044	<.001	.009	3	2
SKIN	GGTLC2 →	+0.024	+4.273	.009	.006	3	1
SKIN	SYT10 →	+0.492	+5.217	<.001	<.001	3	1
SKIN	ANKRD30BL →	+0.085	+4.684	<.001	.002	3	1
SKIN	OR1L3 →	+0.022	+4.415	<.001	.007	3	1
SKIN	AVPR1B →	+0.009	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

ZNF480 survival (RNA) · tumor vs normal (RNA) · all ZNF480 data types