ZNF48

Across TCGA cell cohorts, ZNF48 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,022 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF48-associated GO terms across cancer lineages are Regulation of nucleotide-excision repair, Regulation of chromatin organization, and Symbiont-mediated disruption of host cell PML body. Each is linked with ZNF48 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZNF48-to-partner and partner-to-ZNF48 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of nucleotide-excision repair grouped by ZNF48-low versus ZNF48-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF48→partner) and Y-score (partner→ZNF48) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.125	+0.759	<.001	<.001	3	16
LUNG_SCLC	Regulation of chromatin organization →	+0.131	+0.959	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Symbiont-mediated disruption of host cell PML body →	+0.096	+0.872	<.001	<.001	3	15
BONE	Regulation of DNA repair →	+0.075	+0.882	<.001	<.001	3	14
STOMACH	Epigenetic regulation of gene expression →	+0.077	+0.769	<.001	.003	3	14
BONE	Positive regulation of DNA recombination →	+0.101	+0.922	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,022 associations by consensus.

Regulation of nucleotide-excision repair by ZNF48 expression — LUNG_SCLC

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