ZNF473

Across TCGA patient cohorts, ZNF473 protein abundance is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF473-associated genes across cancer lineages are AGXT2, C17orf102, and SUMO1P4. Each is linked with ZNF473 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF473-to-partner and partner-to-ZNF473 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF473 versus AGXT2 in LSCC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF473→partner) and Y-score (partner→ZNF473) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AGXT2 →	+0.037	+1.717	.004	.005	3	1
LSCC	C17orf102 →	+0.038	+2.725	.007	<.001	3	1
LSCC	SUMO1P4 →	+0.538	+2.149	.001	.002	3	1
LSCC	MTND3P22 →	+0.351	+2.410	.006	<.001	3	1
LSCC	AIPL1 →	+0.048	+2.172	.001	.006	2	1
LSCC	SLC36A2 →	+0.040	+0.971	.006	<.001	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

ZNF473 vs AGXT2 — LSCC

Explore this scatter interactively →