Q-omics provides the consensus-scored MTND3P22 profile across patient tissues and cancer cell-line models. MTND3P22 expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in HNSC. Additionally, MTND3P22 RNA expression shows 5,041 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight HNSC, and STAD as cancer lineages where MTND3P22 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes MTND3P22 survival associations across molecular data types. MTND3P22 RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

MTND3P22 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	11	HNSC (81)	view →

This table ranks reproducible MTND3P22 RNA expression–survival associations across cancer types. High MTND3P22 expression shows unfavorable associations in HNSC, KICH, PCPG, BRCA and KIRC, but favorable associations in OV. The HNSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .016). Together, the overview and detailed table identify HNSC as the clearest survival context for MTND3P22 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.260	0.688	.016	81	view →
KICH	DFS	Tertile	All	0.086	0.897	<.001	72	view →
PCPG	OS	Tertile	All	0.412	0.855	<.001	36	view →
BRCA	OS	Tertile	III,IV	0.682	0.840	.021	24	view →
OV	DFS	Tertile	III,IV	0.254	0.144	.034	18	view →
KIRC	DFS	Tertile	IV	0.100	0.631	.024	18	view →

Pink = unfavorable, green = favorable. all 11 lineages →

MTND3P22-HNSC (OS)

Kaplan–Meier survival curve for MTND3P22 RNA expression in HNSC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with MTND3P22 in patient tissues and cancer cell lines. In patient samples, MTND3P22 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,041	STAD (4758)	view →
RNA	3,594	UCEC (1448)	view →