MTND3P22

Across TCGA pan-cancer cohorts, MTND3P22 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated MTND3P22 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MTND3P22 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTND3P22 expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

HNSC, KICH, and PCPG are the cancer types where MTND3P22 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.260	0.688	.016	81	view →
KICH	DFS	Tertile	All	0.086	0.897	<.001	72	view →
PCPG	OS	Tertile	All	0.412	0.855	<.001	36	view →
BRCA	OS	Tertile	III,IV	0.682	0.840	.021	24	view →
OV	DFS	Tertile	III,IV	0.254	0.144	.034	18	view →
KIRC	DFS	Tertile	IV	0.100	0.631	.024	18	view →
THCA	OS	Tertile	All	0.899	0.977	.009	12	view →
PAAD	OS	Tertile	All	0.186	0.495	.031	9	view →
READ	DFS	Tertile	IV	0.255	0.628	.020	9	view →
KIRP	OS	Tertile	II,III,IV	0.216	0.771	.049	9	view →
LUAD	OS	Tertile	All	0.621	0.838	.041	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

MTND3P22–HNSC (OS)

Open the HNSC breakdown →