Across TCGA patient cohorts, ZNF470 mutation is significantly associated with the RNA expression of many other genes, with 4,722 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF470-associated genes across cancer lineages are RCC1, LIG1, and PLA2R1. Each is linked with ZNF470 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF470-to-partner and partner-to-ZNF470 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF470→partner) and Y-score (partner→ZNF470) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RCC1 →	+0.605	+2.332	<.001	<.001	3	3
UCEC	LIG1 →	+0.579	+1.839	<.001	<.001	3	3
UCEC	PLA2R1 →	-0.366	-1.574	.007	.002	3	3
GBM	AGGF1P8 →	+0.210	+5.584	<.001	.003	3	2
LUSC	OR2M2 →	+0.186	+4.295	<.001	.006	3	2
GBM	OR52J3 →	+0.224	+5.857	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,722 associations by consensus.

Exploration

ZNF470 survival (RNA) · tumor vs normal (RNA) · all ZNF470 data types