Across TCGA patient cohorts, ZNF469 mutation is significantly associated with the RNA expression of many other genes, with 4,096 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF469-associated genes across cancer lineages are GMEB1, HSPA9, and BNIP3L. Each is linked with ZNF469 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF469-to-partner and partner-to-ZNF469 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF469→partner) and Y-score (partner→ZNF469) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	GMEB1 →	+0.245	+1.915	.001	.003	3	4
UCEC	HSPA9 →	+0.411	+2.839	<.001	<.001	3	4
UCEC	BNIP3L →	+0.542	+2.258	<.001	<.001	3	4
UCEC	TCP1 →	+0.343	+1.343	.002	.003	3	4
UCEC	YARS1 →	+0.357	+1.397	<.001	.001	3	4
READ	RNU6-13P →	+0.265	+3.302	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,096 associations by consensus.

Exploration

ZNF469 survival (RNA) · tumor vs normal (RNA) · all ZNF469 data types