Across TCGA patient cohorts, ZNF468 protein abundance is significantly associated with the RNA expression of many other genes, with 297 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF468-associated genes across cancer lineages are USP10, TSC2, and RNF40. Each is linked with ZNF468 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF468-to-partner and partner-to-ZNF468 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF468→partner) and Y-score (partner→ZNF468) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	USP10 →	+0.599	+0.932	.001	<.001	3	1
PDAC	TSC2 →	+0.529	+0.734	.001	.001	3	1
PDAC	RNF40 →	+0.422	+0.796	.008	.001	3	1
PDAC	RPAP1 →	+0.505	+0.915	.005	<.001	3	1
PDAC	PBLD →	+1.362	+0.886	<.001	.001	3	1
PDAC	USP9Y →	-4.252	-0.735	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 297 associations by consensus.

Exploration

ZNF468 survival (RNA) · tumor vs normal (RNA) · all ZNF468 data types