ZNF467

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF467 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ZNF467-associated genes across cancer lineages are CD200R1L, MYOG, and OTOR. Each is linked with ZNF467 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF467-to-partner and partner-to-ZNF467 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD200R1L grouped by ZNF467-low versus ZNF467-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF467→partner) and Y-score (partner→ZNF467) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PANCREASCD200R1L →+0.079+3.539.001.00431
BLOOD_LeukemiaMYOG →+0.033+3.769.001.00831
BLOOD_LeukemiaOTOR →+0.946+3.855<.001.00731
BLOOD_LeukemiaVWC2 →+0.577+3.551<.001.00931
LUNG_SCLCSEMG1 →+0.017+4.169<.001.00131
LUNG_SCLCIL36A →+0.016+4.058<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

CD200R1L by ZNF467 expression — PANCREAS

Box plot of CD200R1L in ZNF467-low vs ZNF467-high samples in PANCREAS.

Explore this box plot interactively →

Exploration