ZNF467

Across TCGA pan-cancer cohorts, ZNF467 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated ZNF467 data layer compared with 6 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in uveal melanoma (UVM), where higher ZNF467 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF467 expression acts as an unfavorable survival marker, although some lineages such as PAAD and CESC show a favorable association.

UVM, LUSC, and PAAD are the cancer types where ZNF467 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Median	All	0.386	0.842	<.001	133	view →
LUSC	OS	Tertile	II,III,IV	0.535	0.717	.010	36	view →
PAAD	DFS	Median	All	0.408	0.179	.001	28	view →
CESC	OS	Tertile	IV	0.844	0.107	.010	24	view →
LUAD	DFS	Median	II,III,IV	0.169	0.334	.009	22	view →
PRAD	DFS	Median	All	0.697	0.877	.004	16	view →
OV	DFS	Median	II,III,IV	0.189	0.135	.038	14	view →
READ	OS	Median	All	0.321	0.726	.013	13	view →
UCEC	OS	Median	IV	0.233	0.583	.033	12	view →
TGCT	DFS	Tertile	All	0.515	0.812	.007	12	view →
MESO	OS	Median	All	0.484	0.293	.007	11	view →
KIRP	OS	Quartile	II,III,IV	0.680	0.928	.011	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

ZNF467–UVM (OS)

Open the UVM breakdown →