ZNF460-AS1

Across TCGA pan-cancer cohorts, ZNF460-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated ZNF460-AS1 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher ZNF460-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ZNF460-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and SKCM show a favorable association.

BLCA, KIRC, and SKCM are the cancer types where ZNF460-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Median	All	0.712	0.518	<.001	107	view →
KIRC	DFS	Tertile	All	0.465	0.712	<.001	88	view →
SKCM	OS	Quartile	III,IV	0.817	0.599	.002	45	view →
THYM	OS	Median	All	1.000	0.760	.002	36	view →
ACC	DFS	Quartile	II,III,IV	0.193	0.596	.009	33	view →
COAD	OS	Tertile	All	0.819	0.908	.003	20	view →
STAD	DFS	Median	III,IV	0.178	0.470	.005	20	view →
PRAD	DFS	Tertile	All	0.756	0.887	.001	16	view →
BRCA	OS	Tertile	IV	0.840	0.409	.015	14	view →
UCS	OS	Median	II,III,IV	0.602	0.270	.018	14	view →
KICH	DFS	Quartile	III,IV	0.181	0.913	.004	11	view →
PAAD	DFS	Median	All	0.353	0.211	.032	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

ZNF460-AS1–BLCA (OS)

Open the BLCA breakdown →