ZNF451

Across TCGA patient cohorts, ZNF451 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,419 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF451-associated proteins across cancer lineages are WRNIP1, XPO1, and YTHDC1. Each is linked with ZNF451 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF451-to-partner and partner-to-ZNF451 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF451 versus WRNIP1 in LSCC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF451→partner) and Y-score (partner→ZNF451) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WRNIP1 →	+0.388	+0.463	<.001	<.001	3	6
LSCC	XPO1 →	+0.239	+0.412	<.001	<.001	3	5
HNSC	YTHDC1 →	+0.308	+0.779	<.001	<.001	3	5
HNSC	ZFR →	+0.317	+0.864	<.001	<.001	3	5
LSCC	PHF3 →	+0.350	+0.541	<.001	<.001	3	5
LSCC	PRPF3 →	+0.269	+0.372	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,419 associations by consensus.

ZNF451 vs WRNIP1 — LSCC

Explore this scatter interactively →