ZNF444P1

Across TCGA pan-cancer cohorts, ZNF444P1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ZNF444P1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher ZNF444P1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ZNF444P1 expression acts as an unfavorable survival marker, although some lineages such as KIRP and HNSC show a favorable association.

KIRP, HNSC, and UCS are the cancer types where ZNF444P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Quartile	All	0.923	0.724	<.001	84	view →
HNSC	OS	Quartile	IV	0.847	0.658	<.001	81	view →
UCS	DFS	Quartile	II,III,IV	0.655	0.168	.001	48	view →
LGG	DFS	Tertile	All	0.576	0.774	<.001	48	view →
CESC	OS	Median	II,III,IV	0.841	0.662	.013	22	view →
SARC	OS	Tertile	All	0.822	0.599	.003	20	view →
LIHC	OS	Median	All	0.853	0.689	.008	14	view →
BRCA	OS	Median	All	0.638	0.528	.025	13	view →
PAAD	DFS	Quartile	All	0.218	0.398	.020	12	view →
ACC	OS	Quartile	III,IV	0.919	0.451	.017	12	view →
OV	OS	Median	IV	0.648	0.843	.011	10	view →
LUAD	OS	Quartile	III,IV	0.569	0.307	.030	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ZNF444P1–KIRP (DFS)

Open the KIRP breakdown →