ZNF444P1

Across TCGA pan-cancer cohorts, ZNF444P1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of ZNF444P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where ZNF444P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ZNF444P1 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

KIRP, KICH, and LUAD are the cancer types where ZNF444P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF444P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	All	+1.072	<.001	6	view →
KICH	Male	All	−0.914	<.001	5	view →
LUAD	Male	All	+0.566	.001	5	view →
UCEC	All	All	−0.896	<.001	4	view →
BRCA	All	All	−0.189	.001	4	view →
THCA	All	All	−0.333	<.001	3	view →
CHOL	Male	All	+1.225	.007	2	view →
PRAD	All	All	−0.499	<.001	2	view →
READ	Female	All	−0.392	<.001	2	view →
HNSC	All	All	+0.324	.039	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

ZNF444P1–KIRP

Open the KIRP breakdown →