ZNF444

Across TCGA patient cohorts, ZNF444 mutation is significantly associated with the RNA expression of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF444-associated genes across cancer lineages are MIR3928, LINC01673, and LINC02839. Each is linked with ZNF444 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF444-to-partner and partner-to-ZNF444 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3928 grouped by ZNF444-low versus ZNF444-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF444→partner) and Y-score (partner→ZNF444) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR3928 →	+1.079	+5.212	<.001	.007	3	2
HNSC	LINC01673 →	+0.080	+5.736	<.001	.003	3	1
HNSC	LINC02839 →	+0.124	+5.655	<.001	.004	3	1
HNSC	MESTP2 →	+0.112	+5.435	<.001	.005	3	1
UCEC	ACER2P1 →	+0.238	+4.026	.003	.006	3	1
UCEC	OR52M1 →	+0.149	+4.038	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

MIR3928 by ZNF444 expression — COAD

Explore this box plot interactively →