ZNF443

Across TCGA pan-cancer cohorts, ZNF443 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ZNF443 data layer compared with 28 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher ZNF443 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF443 expression acts as an unfavorable survival marker.

STAD, COAD, and UCEC are the cancer types where ZNF443 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Median	All	0.199	0.730	.002	12	view →
COAD	DFS	Median	All	0.283	0.699	.001	12	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
LUSC	OS	Median	II,III,IV	0.250	0.778	.007	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ZNF443–STAD (OS)

Open the STAD breakdown →