ZNF443

Across TCGA patient cohorts, ZNF443 mutation is significantly associated with the RNA expression of many other genes, with 1,737 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF443-associated genes across cancer lineages are SNX3P1Y, RNU7-190P, and DNAJA1P1. Each is linked with ZNF443 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF443-to-partner and partner-to-ZNF443 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNX3P1Y grouped by ZNF443-low versus ZNF443-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF443→partner) and Y-score (partner→ZNF443) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNX3P1Y →	+0.080	+4.156	<.001	.004	3	3
SKCM	RNU7-190P →	+0.327	+2.862	<.001	.005	3	3
SKCM	DNAJA1P1 →	+0.015	+3.021	.003	.009	3	3
UCEC	NDUFA6 →	+0.436	+2.180	<.001	.002	3	3
UCEC	RN7SL447P →	+0.157	+2.003	<.001	.007	3	3
SKCM	RNA5SP521 →	+0.180	+4.315	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,737 associations by consensus.

SNX3P1Y by ZNF443 expression — UCEC

Explore this box plot interactively →