ZNF443

Across TCGA cell cohorts, ZNF443 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,242 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF443-associated GO terms across cancer lineages are Chromatin looping, Positive regulation of cytoplasmic mRNA processing body assembly, and Regulation of cytoplasmic mRNA processing body assembly. Each is linked with ZNF443 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF443-to-partner and partner-to-ZNF443 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromatin looping grouped by ZNF443-low versus ZNF443-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF443→partner) and Y-score (partner→ZNF443) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Chromatin looping →	+0.097	+0.675	.002	.008	3	10
BLOOD_Lymphoma	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.122	+1.161	<.001	<.001	3	10
BLOOD_Lymphoma	Regulation of cytoplasmic mRNA processing body assembly →	+0.111	+1.050	<.001	<.001	3	9
SOFT_TISSUE	Intracellular copper ion homeostasis →	-0.138	-0.593	<.001	<.001	3	9
BLOOD_Leukemia	Positive regulation of termination of RNA polymerase II transcription →	+0.093	+0.804	<.001	<.001	3	9
BLOOD_Leukemia	Positive regulation of termination of DNA-templated transcription →	+0.093	+0.804	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,242 associations by consensus.

Chromatin looping by ZNF443 expression — OVARY

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