ZNF440

Across TCGA patient cohorts, ZNF440 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,905 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF440-associated proteins across cancer lineages are HSP90B1, TRIR, and PKP4_S281. Each is linked with ZNF440 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF440-to-partner and partner-to-ZNF440 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF440 versus HSP90B1 in BRCA, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF440→partner) and Y-score (partner→ZNF440) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HSP90B1 →	-0.364	-0.616	<.001	<.001	3	6
OV	TRIR →	+0.445	+1.031	.001	<.001	3	4
BRCA	PKP4_S281 →	+0.876	+0.874	<.001	<.001	3	4
GBM	WIZ →	+0.344	+0.446	<.001	<.001	3	4
GBM	SEC23IP →	-0.264	-0.449	<.001	<.001	3	4
GBM	SP1 →	+0.240	+0.263	.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,905 associations by consensus.

ZNF440 vs HSP90B1 — BRCA

Explore this scatter interactively →