ZNF440

Across TCGA patient cohorts, ZNF440 protein abundance is significantly associated with the RNA expression of many other genes, with 256 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF440-associated genes across cancer lineages are PES1, GCAT, and TXN2. Each is linked with ZNF440 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF440-to-partner and partner-to-ZNF440 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF440 versus PES1 in BRCA, with a Pearson correlation of -0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF440→partner) and Y-score (partner→ZNF440) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PES1 →	-0.550	-0.477	.002	.004	3	1
BRCA	GCAT →	-0.742	-0.466	.001	.005	3	1
BRCA	TXN2 →	-0.565	-0.504	.002	.002	3	1
BRCA	GRAP2 →	+0.845	+0.653	<.001	.006	3	1
BRCA	GCLC →	-0.783	-0.636	.007	.006	3	1
BRCA	IL12B →	+0.540	+0.641	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 256 associations by consensus.

ZNF440 vs PES1 — BRCA

Explore this scatter interactively →