ZNF436

Across TCGA cell cohorts, ZNF436 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,664 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF436-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with ZNF436 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZNF436-to-partner and partner-to-ZNF436 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by ZNF436-low versus ZNF436-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF436→partner) and Y-score (partner→ZNF436) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of myoblast fusion →	+0.084	+0.694	.003	<.001	3	15
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.098	+0.780	.002	.001	3	14
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.085	+0.822	.005	<.001	2	15
STOMACH	Protein polyubiquitination →	+0.060	+0.813	.003	.005	3	13
STOMACH	Regulation of translational initiation →	+0.094	+1.195	<.001	<.001	3	13
STOMACH	Regulation of myoblast fusion →	+0.105	+0.984	.007	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,664 associations by consensus.

Negative regulation of myoblast fusion by ZNF436 expression — STOMACH

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