ZNF436

Across TCGA cell cohorts, ZNF436 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible ZNF436-associated genes across cancer lineages are OPN1LW, PRAMEF19, and OR4S2. Each is linked with ZNF436 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF436-to-partner and partner-to-ZNF436 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPN1LW grouped by ZNF436-low versus ZNF436-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF436→partner) and Y-score (partner→ZNF436) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OPN1LW →	+0.038	+5.169	<.001	.005	3	1
BREAST	PRAMEF19 →	+0.019	+5.169	<.001	.005	3	1
STOMACH	OR4S2 →	+0.015	+4.285	<.001	.007	3	1
STOMACH	OR4P4 →	+0.012	+4.285	<.001	.007	3	1
STOMACH	KRTAP4-8 →	+0.181	+4.129	<.001	.007	3	1
STOMACH	NANOGNB →	+0.047	+4.285	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

OPN1LW by ZNF436 expression — BREAST

Explore this box plot interactively →