Across TCGA cell cohorts, ZNF433 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF433-associated genes across cancer lineages are SPRR1A, TCP10L3, and TAFA1. Each is linked with ZNF433 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF433-to-partner and partner-to-ZNF433 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF433→partner) and Y-score (partner→ZNF433) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SPRR1A →	+0.201	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TCP10L3 →	+0.120	+4.922	<.001	.009	3	1
LARGE_INTESTINE	TAFA1 →	+0.205	+2.688	.004	.008	3	1
LARGE_INTESTINE	C14orf180 →	+0.152	+4.252	<.001	<.001	3	1
LARGE_INTESTINE	CALML5 →	+0.794	+3.584	<.001	.003	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

ZNF433 survival (RNA) · tumor vs normal (RNA) · all ZNF433 data types